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Fig. 4 | BMC Microbiology

Fig. 4

From: Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis

Fig. 4

Phylogenetic tree of the FCT1-region and its relation to phenotypic binding abilities. The phenotypic binding abilities of the SDSE isolates concorded strongly with genetic variations in the FCT1-region. Based on their affinity for fibronectin, collagen and stainless steel, the isolates could be segregated into four distinct categories. Isolates highlighted in green adhered strongly to fibronectin and collagen, whereas isolates highlighted in yellow bound poorly to both substances. The blue marking signifies high-level binding to fibronectin and a low affinity for collagen. Inversely, the isolates highlighted in the red adhered well to collagen, but not to fibronectin. The isolates highlighted in yellow had a strong affinity for stainless steel, whereas the other isolates were characterized by a medium binding ability to stainless steel. Isolates marked with an asterisk had phenotypic binding characteristics deviating from their colour-coded category. Four isolates were phylogenetic outliers. Scale indicates substitutions per site. The phylogenetic tree was constructed in Geneious by global alignment with free end gaps using the Jukes-Cantor genetic distance model [38]. FastTree was used for visualising and tree-rendering [39]

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