Fig. 2
From: Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis
Characterization of the fibronectin and collagen binding T-antigen (FCT) regions. The vast majority of the SDSE-isolates harboured two FCT-regions, denoted FCT1 and FCT2, respectively. Three structurally different variants of the FCT1-region were detected, designated A, B and C. Of these, variant A was identified in 51 out of 53 isolates, although some variations were observed; the fibronectin binding protein Gfba was absent in 24 isolates, whereas Ancillary protein 1 along with the two downstream Sortase enzymes were absent in 11 isolates. The FCT1 variants A, B and C detected in our SDSE isolates resembled the S. pyogenes variants FCT-6, FCT-5 and FCT-1, respectively.15 The FCT2 region had a conserved genetic composition, but was absent in five isolates. The figure is drawn to scale