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Table 3 Comparison of ROC curves

From: 1H NMR spectroscopy-based metabolomics analysis for the diagnosis of symptomatic E. coli-associated urinary tract infection (UTI)

 

Acetate

Trimethylamine

Ac + TMA

 

AUC

95% CI

p value

AUC

95% CI

p value

AUC

95% CI

p value

E. coli-pos vs CTRLs

0.92

0.81-1.0

<0.0001

0.89

0.79-0.99

<0.0001

0.94

0.86-1.0

<0.0001

E. coli-pos vs non-E. coli

0.86

0.74-0.99

<0.0001

0.70

0.50-0.9

<0.0001

0.84

0.70-0.98

0.0003

E. coli-pos vs All

0.89

0.80-0.98

<0.0001

0.80

0.67-0.94

0.0002

0.89

0.80-0.99

<0.0001

  1. Urine samples positive for E. coli infections were compared to CTRLs, non-E. coli and All patients
  2. The area under the curve (AUC), the 95% confidence interval (CI), and the p values are reported. The ROC curves were built using Acetate and Trimethylamine, individually, or combining both concentrations