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Table 4 In vitro activity of antifungal drugs against biofilm forming cells

From: Diversity, in-vitro virulence traits and antifungal susceptibility pattern of gastrointestinal yeast flora of healthy poultry, Gallus gallus domesticus

Yeast species (No. of isolates)

MIC (mg/ml) of biofilm forming cells

Fluconazole

Amphotericin B

Voriconazole

Caspofungin

Interval

MIC50

MIC90

GM

Interval

MIC50

MIC90

GM

Interval

MIC50

MIC90

GM

Interval

MIC50

MIC90

GM

C. albicans (5)

8–256

128

204.8

64

0.5–4

1

3.2

1.3

0.5–8

4

8

2.29

0.062–0.5

0.125

0.5

0.18

D. catenulata (4)

16–256

-

-

45.2

0.5–8

-

-

2

1–2

-

-

1.18

0.125–0.5

-

-

0.25

C. tropicalis (1)

128

-

-

-

16

-

-

-

1

-

-

-

8

-

-

-

D. hansenii (10)

8–512

33

166.4

42.4

0.5–16

1

5.2

1.62

0.125–4

0.5

1.3

0.65

0.125–1

0.5

0.5

0.37

S. catenata (7)

8–512

64

281.6

47.5

1–16

2

8

2.2

0.5–16

0.5

7

1

0.5–4

0.5

2.2

0.74

C. acidothermophilum (1)

128

-

-

-

1

-

-

-

8

-

-

-

0.0625

-

-

-

Trichosporon spp. (3)

16–256

-

-

50.7

4–16

-

-

6.3

0.5–1

-

-

0.62

0.125–0.5

-

-

0.31

G. candidum (4)

16–128

-

-

53.8

1–2

-

-

1.18

0.5–1

-

-

0.59

0.125–1

-

-

0.42

Cryptococus macerans (3)

8–32

-

-

16

1–8

-

-

2.5

1–8

-

-

2

0.125–1

-

-

0.39