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Fig. 9 | BMC Microbiology

Fig. 9

From: Novel synthetic analogues of avian β-defensin-12: the role of charge, hydrophobicity, and disulfide bridges in biological functions

Fig. 9

Chemotactic activity of AvBD-12 analogues for CCR2 transfected CHO-K1 cells and mouse immature dendritic JAWSII cells. Migration of CCR2 transfected CHO-K1 cells (a-c) and mouse immature dendritic JAWSII cells (d-f). The results are expressed as chemotactic index (C.I.): the number of migrated cells induced by AvBD analogues / the number of migrated cells in response to chemotactic buffer. Data are means ± SD (n = 5). Statistical analysis was performed using the one-way analysis of variance (ANOVA) followed by Duncan’s test for multiple comparisons using software SPSS version 19.0 (IBM Corp., Armonk, NY). Asterisks indicate statistically significant difference between analogues and wild-type AvBD-12 (*p < 0.05, **p < 0.01)

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