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Table 1 Minimal bactericidal (MBC) and fungicidal (MFC) concentration (ppm) of compounds tested against selected microorganisms

From: Antimicrobial structure activity relationship of five anthraquinones of emodine type isolated from Vismia laurentii

 

Compounds

A

B

C

D

E

N

G

Yeast

Candida albicans

pH 5

150

600

600

1200

550

25

 

pH 6

300

600

1200

1200

1100

50

 

pH 7

1200

1200

/

1200

1100

25

 

Gram-positive bacteria

Listeria monocytogenes

pH 5

600

/

/

/

/

 

25

pH 6

600

/

/

/

/

 

6.25

pH 7

1200

1200

/

/

/

 

25

Staphylococcus aureus

pH 5

600

1200

1200

/

1100

 

75

pH 6

600

/

1200

/

/

 

˂ 3.12

pH 7

1200

/

75

150

/

 

˂ 3.12

Bacillus cereus

pH 5

300

/

/

/

/

 

˂ 3.12

pH 6

600

/

/

/

/

 

˂ 3.12

pH 7

600

/

/

300

/

 

˂ 3.12

Gram-negative bacteria

Salmonella enteritidis

pH 5

/

/

1200

/

/

 

600

pH 6

/

/

/

/

/

 

600

pH 7

/

/

/

/

/

 

˂ 3.12

Escherichia coli

pH 5

/

/

1200

/

/

 

12.50

pH 6

/

/

/

/

/

 

6.25

pH 7

/

/

/

/

/

 

25

  1. A = 3-geranyloxyemodine, B = vismiaquinone B, C = 3-methoxyemodine, D = 2-isoprenyl-3-methoxyemodine, E = bivismiaquinone, G = gentamicin (antibacterial), N = nystatin (antifungicidal), <= inferior,/= not active at concentration ≤ 1200 ppm