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Table 9 Comparison of the identification efficiency of the two databases per species, using the D1 algorithm of identification with a 1.7 LS threshold, for 180 strains that are represented by three or more strains in both reference databases

From: Decision criteria for MALDI-TOF MS-based identification of filamentous fungi using commercial and in-house reference databases

  

In-House database

Bruker database

 

nb of isolates

% accepted

species PPV

% accepted

species PPV

Absidia corymbifera

2

100.00

1.00

50.00

1.00

Alternaria alternata

2

100.00

0.50

100.00

1.00

Aspergillus flavus

15

100.00

1.00

73.33

1.00

Aspergillus fumigatus

20

95.00

1.00

45.00

1.00

Aspergillus nidulans

8

100.00

1.00

75.00

1.00

Aspergillus niger

4

100.00

1.00

50.00

1.00

Aspergillus parasiticus

2

100.00

1.00

0.00

Not Relevant

Aspergillus terreus

10

100.00

1.00

30.00

1.00

Aspergillus versicolor

3

66.67

1.00

33.33

1.00

Exophiala dermatitidis

2

50.00

1.00

50.00

1.00

Fusarium oxysporum

21

80.95

1.00

19.05

1.00

Fusarium proliferatum

10

100.00

1.00

60.00

0.33

Fusarium solani

7

57.14

0.25

28.57

1.00

Microsporum canis

2

100.00

1.00

50.00

1.00

Purpureocillium lilacinus

3

66.67

1.00

66.67

1.00

Paecilomyces variotii

3

66.67

1.00

66.67

1.00

Penicillium chrysogenum

27

100.00

0.96

33.33

1.00

Scedosporium apiospermum

11

100.00

0.82

81.82

1.00

Schizophyllum commune

4

100.00

1.00

100.00

1.00

Scopulariopsis brevicaulis

15

86.67

1.00

46.67

0.71

Trichophyton interdigitale

1

100.00

1.00

0.00

Not Relevant

Trichophyton rubrum

8

87.50

0.86

37.50

0.67

Total Isolates

180

91.67

0.95

47.22

0.92

  1. Nb of isolates : number of isolates from the panel of strain that belong to each species. % accepted: percentage of submitted strains that fulfilled the criteria for identification at either the genus or species level; species PPV: positive predictive value at the species level