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Fig. 3 | BMC Microbiology

Fig. 3

From: Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae

Fig. 3

Time-kill curves for the Neisseria gonorrhoeae DG666 strain using eight different antimicrobials. The antimicrobial susceptible strain DG666 was exposed to the antimicrobials gentamicin (a), spectinomycin (b), azithromycin (c), benzylpenicillin (d), ceftriaxone (e), cefixime (f), chloramphenicol (g) and tetracycline (h). Twelve doubling dilutions are plotted, the highest concentration (black line) corresponds to 16× MIC as measured with Etest and growth in absence of antimicrobial is drawn in red. The antimicrobial was added at timepoint 0 and monitored until 6 h. The limit of detection in the assay was 100 CFU/ml. Data from one of two independent experiments are shown. Additional data are available on GitHub [21]

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