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Table 1 Growth rate and biomass yield for dme, pck, and pyk mutants of both strain variants, base cases included, marked asa

From: Difference in C3–C4 metabolism underlies tradeoff between growth rate and biomass yield in Methylobacterium extorquens AM1

Strain + medium condition

Biomass yield (g cdw/mol methanol consumed)

Absolute change in biomass yield

(g cdw/mol methanol consumed)

Percent of original strain biomass yield under same condition

Growth rate (per hr)

Absolute change in growth rate(per hr)

Percent of original strain growth under same condition

LL + HY

8.90 ± 0.59

a

a

0.09 ± 0.01

a

a

VL + HY

6.44 ± 0.90

a

a

0.13 ± 0.01

a

a

LL + HYC

6.09 ± 0.04

a

a

0.13 ± 0.01

a

a

VL + HYC

4.38 ± 0.31

a

a

0.15 ± 0.01

a

a

LL: Dpck + HY

4.84 ± 0.98

−4.07

54 % ± 11 %

0.10 ± 0.01

0.01

111 % ± 12 %

VL: Dpck + HY

5.26 ± 0.52

−1.17

82 % ± 8 %

0.10 ± 0.01

−0.03

77 % ± 8 %

LL: Dpck + HYC

4.76 ± 1.67

−1.33

78 % ± 27 %

0.09 ± 0.01

−0.04

75 % ± 10 %

VL: Dpck + HYC

5.06 ± 0.49

0.68

115 % ± 11 %

0.09 ± 0.01

−0.06

60 % ± 8 %

LL: Ddme + HY

4.07 ± 2.06

−4.83

46 % ± 23 %

0.09 ± 0.01

0

100 % ± 10 %

VL: Ddme + HY

4.62 ± 1.02

−1.81

72 % ± 16 %

0.09 ± 0.01

−0.04

69 % ± 8 %

LL: Ddme + HYC

5.92 ± 0.37

−0.16

97 % ± 6 %

0.07 ± 0.01

−0.06

58 % ± 10 %

VL: Ddme + HYC

6.01 ± 0.76

1.63

137 % ± 17 %

0.10 ± 0.01

−0.05

67 % ± 7 %

LL: Dpyk + HY

7.77 ± 0.45

−1.13

87 % ± 6 %

0.10 ± 0.01

0.01

108 % ± 6 %

VL: Dpyk + HY

6.30 ± 0.17

−0.14

98 % ± 4 %

0.06 ± 0.01

−0.07

44.9 % ± 6 %

LL: Dpyk + HYC

7.60 ± 0.56

1.51

125 % ± 8 %

0.11 ± 0.01

−0.02

86 % ± 10 %

VL: Dpyk + HYC

6.63 ± 1.14

2.25

151 % ± 17 %

0.10 ± 0.01

−0.05

63 % ± 10 %