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Table 1 Wild type and mutant S. pneumoniae strains used

From: Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes

Strain

Capsule serotype

Description

B201.73

19F

Wild types (clinical isolates) [12]

103.57

23F

B101.77

14

307.14

18C

109.74

9V

207.31

15

106.66

6B

208.41

7F

P21

3

Wild type [13]

106.66 Janus

nonencapsulated

Capsule operon replaced by a Janus cassette [12]

106.66cps106.66

6B

Capsule switch mutants [12]

106.66cpsB201.73

19F

106.66cps103.57

23F

106.66cpsB101.77

14

106.66cps307.14

18C

106.66cps109.74

9V

106.66cps207.31

15

106.66cps208.41

7F

B103.21

1

Wild type, non-haemolytic (current study)

211.25

1

Wild type, poorly haemolytic (current study)

207.06

1

Wild type, haemolytic (current study)

202.67

1

Wild type, non-haemolytic (current study)

D39

2

Wild type [11]

D39Δply

2

Mutant lacking pneumolysin [11]

D39Δcps

nonencapsulated

Mutant lacking capsule [11]

D39ΔplyΔcps

nonencapsulated

Mutant lacking pneumolysin and capsule [11]