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Fig. 5 | BMC Microbiology

Fig. 5

From: E2 multimeric scaffold for vaccine formulation: immune response by intranasal delivery and transcriptome profile of E2-pulsed dendritic cells

Fig. 5

RNA-Seq analysis of E2-pulsed BMDCs. a Standard MA plot (“ratio intensity plot”) of the FPKM (Fragments Per Kilobase of transcript and Million of mapped reads) of E2-pulsed bone marrow-derived dendritic cells (BMDCs) vs untreated cells per each RefSeq gene. The y-axis represents the fold change (M = Log Ratio) and the x-axis the Average Intensity (A) for each gene (dot). Gray dots indicate differentially expressed (DE) genes. b Heatmap showing the fold change in gene expression for selected DE genes in E2-pulsed BMDCs vs untreated cells. Green asterisks include Th2 and MHC-II related genes; red asterisks include Th1-associated genes

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