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Table 3 Univariate analysis of risk factors for fecal colonization by CPE among ICU patients

From: Risk factors for fecal carriage of carbapenemase producing Enterobacteriaceae among intensive care unit patients from a tertiary care center in India

RISK Factors

Total Patients N = 100

P value

Odds Ratio

Confidence Interval

No of patients

Patients with CPE (n = 26) (%)

Patients without CPE (n = 74) (%)

Sex (Male)

58

17 (65.3)

41 (55.4)

0.37

1.52

0.600

3.849

Antibiotics use

 Carbapenems

14

7 (26.9)

7 (9.5)

0.027

3.528

1.1

11.304

 Cephalosporins

45

13 (50)

32 (43.2)

0.55

1.313

0.536

3.125

 Aminoglycosides

11

6 (23.1)

5 (6.8)

0.032

4.14

1.143

14.994

 Augmentin

5

1 (3.8)

4 (5.4)

0.75

0.700

0.075

6.565

 Fluoroqinolones

9

3 (11.5)

6 (8.1)

0.59

1.478

0.342

6.393

Interventions used

 Central venous line

35

12 (46.2)

23 (31.1)

0.16

1.901

0.761

4.744

 Ventilator

61

21 (80.8)

40 (54.1)

0.01

3.570

1.216

10.483

 Peripheral catheter

83

22 (84.6)

61 (82.4)

0.79

1.172

0.345

3.978

 Naso-gastric tube

43

15 (57.7)

28 (37.8)

0.07

2.240

0.903

5.559

 Oxygen Mask

21

6 (23.1)

15 (20.3)

0.7

1.180

0.403

3.454

Co-morbid conditions

 Surgery

15

7 (26.9)

8 (10.8)

0.048

3.039

0.976

9.461

 Chronic lung disease

20

2 (7.7)

18 (24.3)

0.06

0.259

0.056

1.206

 Neoplasia

7

1 (3.8)

6 (8.1)

0.4

0.453

0.052

3.955

Multivariate analysis

 Ventilator

 

0.027

0.291

0.097

0.871

 Aminoglycosides

 

0.046

0.257

0.068

0.975

  1. CPE carbapenemase producing Enterobacteriaceae