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Table 1 Estimated growth parameters and prior growth parameters of ten E. coli strains used in the model for competitive growth

From: Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment

Strain

MIC-tet μg/ml

MIC-amp μg/ml

Combination

Parameter Coefficients

Priors

αmax

EC50tet

γtet

EC50amp

γamp

EC50tet

γtet

EC50amp

γamp

A

2.00

1.00

STSA

1.93

1.14

8.35

0.81

2.05

1.14

8.35

0.67

1.92

B

128

4.00

RTSA

1.93

74.03

11.24

5.21

7.03

74.03

11.24

2.53

5.00

C

0.50

1024

STRA

1.81

0.24

1.35

440

5.14

0.15

1.87

440.7

5.14

D

512

1024

RTRA

1.77

187

3.99

400

5.00

186.9

3.99

400

5.00

E

64

8.00

RTSA

2.03

67.5

8.23

4.95

4.84

67.46

8.23

2.85

3.96

F

0.50

4.00

STSA

2.05

0.32

2.42

4.70

5.03

0.23

2.80

2.33

4.00

G

0.50

8.00

STSA

1.93

0.24

1.73

3.59

4.43

0.18

2.24

3.62

4.42

H

16

2.00

RTSA

1.73

9.24

13.95

1.33

1.53

9.24

13.95

1.29

5.00

I

0.50

256

STRA

1.84

0.20

1.26

151.5

5.00

0.14

1.72

151.5

5.00

J

0.25

2.00

STSA

1.76

0.12

1.24

0.46

2.64

0.11

1.83

0.64

2.32