Table 1 Effect of TZ on EP substrates MICs before and after the exposure processes
From: Impact of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus
MIC (mg/L) after exposure to: | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ | á…Ÿ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | EtBr | CIP | CET | |||||||||
|  | Original MIC (mg/L) | ½ MIC | MIC | ½ MIC | MIC | ½ MIC | MIC | |||||||
| Â | No EI | + TZ | No EI | + TZ | No EI | + TZ | No EI | + TZ | No EI | + TZ | No EI | + TZ | No EI | + TZ |
ATCC25923 | ||||||||||||||
EtBr | 8 | 1 (↓8x) | 32 | 4 (↓8x) | 32 | 1 (↓32x) | 32 | 8 (↓4x) | 32 | 4 (↓8x) | 8 | 2 (↓4x) | 32 | 4 (↓8x) |
CIP | 0.25 | 0.125 (↓2x) | 2 | 0.25 (↓8x) | 2 | 0.25 (↓8x) | 2 | 0.5 (↓4x) | 2 | 0.5 (↓4x) | 0.5 | 0.25 (↓2x) | 2 | 0.5 (↓4x) |
CET | 2 | 0.25 (↓8x) | 4 | 0.5 (↓8x) | 8 | 0.125 (↓64x) | 4 | 0.5 (↓8x) | 4 | 0.5 (↓8x) | 4 | 0.5 (↓8x) | 4 | 0.5 (↓8x) |
SM2 | ||||||||||||||
EtBr | 8 | 2 (↓4x) | 32 | 1 (↓32x) | 64 | 2 (↓32x) | 32 | 4 (↓8x) | 32 | 2 (↓16x) | 8 | 1 (↓8x) | 32 | 4 (↓8x) |
CIP | 32 | 16 (↓2x) | 128 | 16 (↓8x) | 512 | 32 (↓16x) | 256 | 32 (↓8x) | 256 | 16 (↓16x) | 32 | 8 (↓4x) | 128 | 32 (↓4x) |
CET | 2 | 0.5 (↓4x) | 4 | 0.25 (↓16x) | 16 | 4 (↓4x) | 4 | 2 (↓2x) | 8 | 1 (↓8x) | 4 | 0.5 (↓8x) | 8 | 2 (↓4x) |
SM50 | ||||||||||||||
EtBr | 8 | 1 (↓8x) | 64 | 8 (↓8x) | 32 | 8 (↓4x) | 64 | 4 (↓16x) | 32 | 4 (↓8x) | 16 | 2 (↓8x) | --- | --- |
CIP | 64 | 16 (↓4x) | 256 | 64 (↓4x) | 256 | 64 (↓4x) | 512 | 64 (↓8x) | 256 | 64 (↓4x) | 128 | 32 (↓4x) | --- | --- |
CET | 4 | 0.5 (↓8x) | 8 | 1 (↓8x) | 8 | 1 (↓8x) | 8 | 2 (↓4x) | 8 | 2 (↓4x) | 4 | 1 (↓4x) | --- | --- |