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Fig. 5 | BMC Microbiology

Fig. 5

From: Comparative analysis of the growth and biological activity of a respiratory and atheroma isolate of Chlamydia pneumoniae reveals strain-dependent differences in inflammatory activity and innate immune evasion

Fig. 5

Histopathological changes in the lungs of mice infected with C. pneumoniae strains AO3 or AR39. C57BL/6 mice were intranasally infected with C. pneumoniae strain AO3 or AR39, or mock infected; at designated time points (day 3, day 9 and day 22), mice were euthanized and the lungs were processed, as described in the Methods section. a-f Representative images of H&E stained lung tissue from 1 μm resin-embedded sections; n = 3 mice per group. Arrow heads identify areas of inflammation while the arrows identify normal lung. g Quantified inflammation area from lung sections was generated using Image-J software analyzing both lungs, n = 3 mice per group. Significance: *, p ≤ 0.05. Data is representative of 2 independent experiments

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