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Fig. 3 | BMC Microbiology

Fig. 3

From: Differential replicative ability of clinical dengue virus isolates in an immunocompetent C57BL/6 mouse model

Fig. 3

Antibody-dependent enhancement (ADE) of infection of C57BL/6 mice macrophages with DENV-1 and DENV-2. The enhancement of infection was evaluated by the quantification of the viral titer in the supernatant of the macrophage cultures 48 h post-infection with the Mochizuki strain and the D2/BR/RP/RMB/2009 isolate, which were previously incubated with 1:5000 dilutions of DENV-2 and DENV-1 immune sera, respectively. Data represent the mean values ± SD. The results are representative of two similar and independent experiments. ***p < 0.01 when viruses incubated with heterologous immune sera were compared to viruses incubated with PBS

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BMC Microbiology

ISSN: 1471-2180

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