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Fig. 2 | BMC Microbiology

Fig. 2

From: Differential replicative ability of clinical dengue virus isolates in an immunocompetent C57BL/6 mouse model

Fig. 2

Antibody-dependent enhancement (ADE) of infection of C57BL/6 mice macrophages with DENV-3. The enhancement of infection was evaluated by quantification of the viral titer in the supernatant of the macrophage cultures 48 h post-infection with the D3/BR/SL3/02 isolate, which was previously incubated with different dilutions of DENV-1 immune serum (1:10, 1:100, 1:1000, 1:2000, 1:5000, 1:10000 and 1:100000). Data represent the mean values ± SD. The results are representative of two similar and independent experiments. ***p < 0.001 when the virus incubated with DENV-1 immune serum was compared to the virus incubated with PBS or naive serum

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