Skip to main content

Table 2 Correlations between bacterial growth inhibition and soluble factors

From: Leukocyte presence does not increase microbicidal activity of Platelet-rich Plasma in vitro

Bacteria

Time

Soluble factors

  

CCL3/MIP-1α

CCL-5/RANTES

CXCL1/GRO-α

CXCL-8/IL-8

CXCL-7/NAP2

CXCL-12/SDF-1α

IL-6

Escherichia coli

1 h

---

---

---

---

---

p < 0.05

---

2 h

---

p < 0.05

p < 0.05

---

---

p < 0.005

---

4 h

---

---

p < 0.01

---

---

---

---

Staphylococcus aureus

1 h

p < 0.01

---

p < 0.0001

---

p < 0.01

---

---

2 h

p < 0.005

p < 0.01

---

p < 0.01

p < 0.000005

p < 0.05

---

4 h

p < 0.005

p < 0.05

---

p < 0.01

p < 0.00001

---

---

Klebsiella pneumoniae

1 h

---

p < 0.000005

p < 0.01

p < 0.01

p < 0.001

p < 0.0001

p < 0.01

2 h

p < 0.01

---

---

---

---

---

---

4 h

p < 0.01

p < 0.05

---

p < 0.005

p < 0.000005

p < 0.001

p < 0.005

Pseudomonas aeruginosa

1 h

---

---

---

---

---

---

---

2 h

p < 0.000005

p < 0.0005

 

p < 0.01

p < 0.000005

p < 0.005

p < 0.0001

4 h

p < 0.0005

p < 0.0005

p < 0.05

p < 0.005

p < 0.000005

p < 0.001

p < 0.0005

Enterococcus faecalis

1 h

---

---

---

---

p < 0.005

---

---

2 h

p < 0.000005

p < 0.00005

p < 0.05

p < 0.001

p < 0.0005

p < 0.00005

p < 0.000005

4 h

p < 0.05

---

---

---

---

---

---

  1. Significant correlations between bacterial growth inhibition at different time points and the concentration of soluble factors released by the PRP preparations after 1 h of activation and described with antimicrobial potential, as determined by Kendall-Tau rank correlation test