Skip to main content
Fig. 2 | BMC Microbiology

Fig. 2

From: Antimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilms

Fig. 2

Effect of peptide treatment (at 10 times the planktonic MIC) on P. aeruginosa biofilms. Biofilms were grown in (a) microtiter plates (static conditions) and antibiofilm activities were determined by the MTT assay (disinfecting activity) and CV stain (removal activity); (b) CDC-reactor (turbulent conditions) and treated with 10 times the MIC of the indicated compound for 24 h at 37 °C. Live cells show green fluorescence due to GFP expression, whereas dead cells appear red because of the uptake of propidium iodide. Sodium hypochlorite at 500 μg/ml was used as an antimicrobial positive control. Scale Bars = 20 μm. LF-322 treated biofilms were not selected for fluorescence analysis since no activity against biofilm in microplates assays was found

Back to article page