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Table 2 CLSI (document M27-S4) and EUCAST (version 6.1) antifungal breakpoints for Candida species

From: Susceptibility to echinocandins of Candida spp. strains isolated in Italy assessed by European Committee for Antimicrobial Susceptibility Testing and Clinical Laboratory Standards Institute broth microdilution methods

 

MIC (μg/ml) breakpoint for susceptibility/resistance

Species

Anidulafungin

Caspofungin

Micafungin

C. albicans

   

CLSI

≤0.25/≥1

≤0.25/≥1

≤0.25/≥1

EUCAST

≤0.03/>0.03

≤0.016/>0.016

C. parapsilosis

   

CLSI

≤2/≥8

≤2/≥8

≤2/≥8

EUCAST

≤0.002/>4

≤0.002/>2

C. glabrata

   

CLSI

≤0.12/≥0.5

≤0.12/≥0.5

≤0.06/≥0.25

EUCAST

≤0.06/>0.06

≤0.03/>0.03

C. tropicalis

   

CLSI

≤0.25/≥1

≤0.25/≥1

≤0.25/≥1

EUCAST

≤0.06/>0.06

C. gulliermondii

   

CLSI

≤2/≥8

≤2/≥8

≤2/≥8

EUCAST

C. krusei

   

CLSI

≤0.25/≥1

≤0.25/≥1

≤0.25/≥1

EUCAST

≤0.06/>0.06

  1. “−” denotes that no breakpoints have yet been established