Extensive characterization of Campylobacter jejuni chicken isolates to uncover genes involved in the ability to compete for gut colonization

Table 5 Genes associated with Campylobacter jejuni strains possessing lower potential competition capacities

Gene	Rank	Agg	Chm	Inv	Adh	Function
Gene	p value	p value	p value	p value	p value	Function
lctP	0.002	0.222	0.018	0.037	0.023	L-lactate permease
CJ1325	0.003	0.538	0.001	0.054	0.112	Putative periplasmic protein
CJE1277	0.004	0.538	0.002	0.037	0.087	Putative glycosyltransferase
CJE0171	0.006	0.796	0.003	0.070	0.049	Putative TonB-dependant outer membrane receptor
CJE1679	0.009	0.436	0.147	0.017	0.011	Methyl-accepting chemotaxis protein
CJ0223	0.010	0.983	0.037	0.002	0.266	Pseudogene, putative IgA protease family protein
motA	0.010	0.920	0.002	0.085	0.143	Flagellar motor proton channel possible variant
CJE1820	0.012	0.885	0.011	0.019	0.039	Putative periplasmic protein
CJE1730	0.021	0.645	0.015	0.068	0.041	Putative permease
cfrA	0.030	0.677	0.008	0.218	0.233	Ferric receptor cfrA
CJE1719	0.039	0.213	0.069	0.025	0.008	Zinc-binding dehydrogenase family oxidoreductase variant

In the characterized C. jejuni strain collection, strains positive by microarray for these genes had lower mean rank values then the negative strains, as assessed by the Mann–Whitney test. An alpha value lower than 0.05 was considered for genes present in strains likely to possess different mean rank values or phenotypical properties, while an alpha value lower than 0.002 was considered for identifying genes that are of greater importance; Phenotypic properties refer to Agg = autoagglutination; Chm = chemotaxis; Inv = invasion; Adh = adhesion.

ISSN: 1471-2180