Figure 1

V. vulnificus genes showing altered expression in the ΔvarA mutant as determined by comparative transcriptome analysis with wild type. A - A diagram of the down-regulated V. vulnificus genes in the ΔvarA mutant. When the normalized expression relative to wild type was confined to be <0.5 with a statistical significance [P-value <0.05 by one-sample Student t-test using MultiExperiment Viewer (The Institute for Genome Research, http://www.tm4.org/mev.html) 4.8.1 version], 110 gene were selected and then divided into four functional categories, i.e., metabolism, cellular process, information process, and poorly characterized genes. For each category, representative genes are presented along with the percentage; B - A diagram of the up-regulated V. vulnificus gene in the ΔvarA mutant. When the normalized expression relative to wild type was confined to be <2 with a statistical significance [P-value <0.05 by one-sample Student t-test using MultiExperiment Viewer (The Institute for Genome Research, http://www.tm4.org/mev.html) 4.8.1 version], 57 genes were selected and then divided into four functional categories, i.e., metabolism, cellular process, information process, and poorly characterized genes. For each category, representative genes are presented along with the percentage.