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Table 2 Viable count (CFUs; means ± SEM) of H. pylori strains in G. mellonella at 24, 48 and 72 h post-infection

From: Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori

Strains

T0

24 h

48 h

72 h

G27

1.1 (±0.06) × 106

3.9 (±0.03) × 106

5.2 (±0.8) × 106

1.6 (±0.3) × 107

G27Δcag A

1.6 (±0.2) × 106

2.8 (±0.06) × 106

4.6 (±0.4) × 106

1.1 (±0.2) × 107

G27Δcag E

1.0 (±0.1) × 106

2.2 (±0.04) × 106

4.0 (±0.6) × 106

9.2 (±0.3) × 106

G27ΔcagPAI

1.2 (±0.3) × 106

2.0 (±0.02) × 106

3.6 (±0.4) × 106

8.6 (±0.2) × 106

60190

1.6 (±0.1) × 106

5.2 (±0.02) × 106

7.8 (±0.1) × 106

1.8 (±0.9) × 107

60190ΔvacA

8.4 (±0.2) × 105

1.9 (±0.04) × 106

3.9 (±0.1) × 106

9.4 (±0.3) × 106

60190ΔcagA

1.2 (±0.1) × 106

2.1 (±0.05) × 106

4.2 (±0.2) × 106

1.2 (±0.3) × 107

60190ΔcagE

1.0 (±0.04) × 106

1.8 (±0.03) × 106

3.4 (±0.4) × 106

1.0 (±0.3) × 107

60190Urease-negative

1.4 (±0.06) × 106

2.6 (±0.2) × 106

4.9 (±0.4) × 106

9.8 (±0.2) × 106

M5

1.3 (±0.04) × 106

2.0 (±0.4) × 106

4.2 (±0.5) × 106

1.2 (±0.2) × 107

M5ggt::aph

1.2 (±0.04) × 106

1.8 (±0.2) × 106

3.6 (±0.6) × 106

9.6 (±0.4) × 106

  1. The number of viable bacteria in infected larvae were determined as described in the Methods section and expressed in CFUs.