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Table 1 Identification of putative C. difficile SrtB substrates in strain 630

From: Clostridium difficilehas a single sortase, SrtB, that can be inhibited by small-molecule inhibitors

Protein

Function

C-terminal sorting signal

CD630_01830

Putative cell wall hydrolase

MIHSPSTGKTVSVTSINSSYYTARFVTA KRIL

CD630_03860

Putative cell surface protein, collagen binding protein

PSDSPKTGDNTNLYGLLALLLTSGAGLAGIFFY KRRKMKKS

CD630_25370

Putative membrane-associated 5'-nucleotidase/phosphoesterase

KEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK

CD630_27680

Putative cell-wall hydrolase

FIHSPQTGDVVKVTSMAPGTNYA RRLITATRVLQ

CD630_28310

Putative adhesion, collagen binding protein

PPVPPKTGDSTTIIGEILLVIGAIVGLIVL RRNKNTN

CD630_31450

Collagen binding protein, CbpA

VGQNVQTGDQSNIMLDLALMFISLFFLI KNLTNKYLRRK

CD630_32460

Putative surface protein

IVKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN

CD630_33920

Putative cell surface protein, collagen binding protein

PSDSPKTGDSTNLMAFIVMLLVSGGGLAGTYLY KRRKMKKS

  1. Bold = predicted sortase recognition sequence.
  2. Bold and Italic = hydrophobic residues.
  3. Italics only = positively charged residues.