Histological findings during the infection of C. callosus with P. brasiliensis. The tissue sections of liver, pancreas, lung, spleen and lymph nodes were stained with haematoxylin-eosin and examined at 200× (A, B, C and F) or 100× (D and E) magnification. In A and B, liver and spleen 15 days post infection, respectively; C and D mesenteric lymph nodes and lung 45 days post infection, respectively; and in E and F, spleen and liver at 75 days post infection. Fungi cells are pointed with arrowheads. Giant cells are pointed with arrows.