Table 2 Up-regulated genes. Functional classes of genes shown are ordered by the S score of the most highly regulated examples in the class with S score ≥ 5.

Chemokine

CCL20

Chemokine (C-C Motif) Ligand 20

13.542

CXCL3

Chemokine (C-X-C Motif) Ligand 3

11.866

CXCL2

Chemokine (C-X-C Motif) Ligand 2

11.742

IL8

Interleukin 8

11.393

CXCL1

Chemokine (C-X-C Motif) Ligand 1

11.096

CXCL6

Chemokine (C-X-C Motif) Ligand 6

10.79

CCL2

Chemokine (C-C Motif) Ligand 2

5.294

TNF/NFkB superfamily

TNFAIP3

Tumor Necrosis Factor, Alpha-Induced Protein 3

11.678

IKBA

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

10.956

TNIP1

TNFAIP3 Interacting Protein 1

9.344

TNFAIP2

Tumor Necrosis Factor, Alpha-Induced Protein 2

8.293

OPTN

Optineurin

6.487

IL32

Interleukin 32

6.12

NFKB1

Nuclear Factor Kappa B (P105)

Apoptosis/Cell death

UBD

Ubiquitin D

11.647

BIRC3

Baculoviral IAP Repeat-Containing 3

11.063

CFLAR

CASP8 And FADD-Like Apoptosis Regulator

6.224

SGK

Serum/Glucocorticoid Regulated Kinase

5.705

ISG20

Interferon Stimulated Exonuclease Gene 20 kda

5.575

Extracellular Matrix

MMP7

Matrix Metallopeptidase 7 (Matrilysin, Uterine)

9.812

SDC4

Syndecan 4 (Amphiglycan, Ryudocan)

8.923

LAMA3

Laminin, Alpha 3

5.824

LAMC2

Laminin, Gamma 2

5.32

Folate receptor

FOLR1

Folate Receptor 1 (Adult)

8.963

Redox state

SOD2

Superoxide Dismutase 2, Mitochondrial

8.879

TXNRD1

Thioredoxin Reductase 1

6.378

Cell adhesion

ICAM1

Intercellular Adhesion Molecule 1

8.879

FNDC3B

Fibronectin Type III Domain Containing 3B

5.851

Cytokines/Receptors

IFNGR1

Interferon Gamma Receptor 1

8.403

CSF2

Colony Stimulating Factor 2

5.101

PLAT

Plasminogen Activator, Tissue

7.464

SERPINB2

Serpin Peptidase Inhibitor 2

6.319

Energy metabolism

ATP1B1

Atpase, Na+/K+ Transporting, Beta 1 Peptide

7.184

Nuclear transcription

CEBPD

CCAAT/Enhancer Binding Protein Delta

6.708

RARRES1

Retinoic Acid Receptor Responder

6.179

Antibacterial

LCN2

Lipocalin 2

6.6

PI3

Peptidase Inhibitor 3 (Elafin)

5.057

Cell signalling

CDC42

Cell Division Cycle 42

7.28

DUSP5

Dual Specificity Phosphatase 5

6.541

SGPL1

Sphingosine-1-Phosphate Lyase 1

6.242

Cytoskeleton/cytokinesis

TPM1

Tropomyosin 1

5.689

PDLIM5

PDZ And LIM Domain 5

5.169

Transcription, protein synthesis and export

SF3B1

Splicing Factor 3b, Subunit 1,

5.146

UGCG

UDP-Glucose Ceramide Glucosyltransferase

5.388

Cell cycle

PLK2

Polo-Like Kinase 2

5.55

Structural

SYNGR3

Synaptogyrin 3

5.133

Antigen presentation

TAP1

Transporter 1, ATP-Binding Cassette

5.207