Subgingival bacterial colonization profiles correlate with gingival tissue gene expression

BMC Microbiology

Table 4 Patterns of gene expression in gingival tissues, according to subgingival levels of A. actinomycetemcomitans, P. gingivalis, T. forsythia and T. denticola.

	A. actinomycetemcomitans	P. gingivalis	T. forsythia	T. denticola
1	antigen processing and presentation	1	1	1
2	apoptotic mitochondrial changes	96	101	96
3	antigen processing and presentation of peptide antigen	3	3	3
4	antigen processing and presentation of peptide antigen via MHC class I	4	3	5
5	phosphate transport	56	63	71
6	muscle development	38	39	44
7	MAPKKK cascade	5	4	7
8	protein-chromophore linkage	152	150	147
9	hemopoietic or lymphoid organ development	9	11	10
10	hemopoiesis	11	12	11
11	immune system development	8	10	9
12	protein amino acid N-linked glycosylation	50	81	52
13	fatty acid biosynthetic process	17	21	8
14	regulation of anatomical structure morphogenesis	7	6	7
15	acute inflammatory response	24	18	21
16	humoral immune response	37	40	35
17	activation of immune response	62	58	54
18	regulation of cell adhesion	51	45	47
19	regulation of cell differentiation	2	2	2
20	hemostasis	12	15	14

The left column lists the top 20 differentially expressed Gene Ontology (GO) groups, according to levels of A. actinomycetemcomitans while columns to the right describe the ranking of these particular GO groups for the other three species.

ISSN: 1471-2180