malT knockout mutation invokes a stringent type gene-expression profile in Actinobacillus pleuropneumoniae in bronchoalveolar fluid

Table 2 Number of genes expressed differentially* within a functional category by the BALF-exposed malT mutant

Functional category	Up-regulated genes	Down-regulated genes
Protein biosynthesis	2	7
Amino acid biosynthesis	6	2
Cofactor biosynthesis	4	8
Biofilm formation	4	0
Nucleotide biosynthesis	3	0
Lipid biosynthesis	0	2
Lipid degradation	1	0
Cell envelope biosynthesis	3	10
Cellular processes	5	2
Central intermediary metabolism	0	4
DNA metabolism	3	6
Energy metabolism	7	18
Protein folding and stabilization	2	2
Regulatory proteins	7	2
Transcriptional regulators	0	5
Secretion and trafficking	4	10
Mobile and extra-chromosomal function	2	0
Unclassified and unknowns	51	41
Total	104	119

* Differential expression of a gene in the malT mutant is relative to the level of expression of the gene in the wild-type organism, as measured in microarray experiments.

ISSN: 1471-2180