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Table 4 Antimicrobial compounds having significantly lower MICs in isolates able to grow in beer.

From: Susceptibility of Pediococcus isolates to antimicrobial compounds in relation to hop-resistance and beer-spoilage

Antimicrobial compound

Median and Distribution of MIC (μg/ml)

p-valuea

 

Grow in Beer

Cannot grow in beer

 

Ampicillin

0.25 (0.12-4)

2 (0.12-4)

< 0.01

Ciprofloxacin

2 (0.5-NRb)

4 (0.5-NR)

< 0.01

Gatifloxacin

1 (0.25-8)

4 (1-NR)

< 0.01

Levofloxacin

2 (0.5-NR)

16 (1-NR)

< 0.05

Oxacillin + 2% NaCl

0.25 (0.25-4)

1 (0.25-NR)

< 0.02

Penicillin

0.12 (0.12-NR)

1 (0.06-NR)

< 0.01

Synercid

0.5 (0.12-1)

1 (0.25-2)

< 0.05

Trimethoprim/Sulfamethoxazole

0.5/9.5 (0.5/9.5-NR)

R (0.5/9.5-NR)

< 0.05

  1. ap-value corresponds to U-test statistic as derived from the non-parametric Mann-Whitney U-test which is designed to examine whether two samples of observations came from the same distribution.
  2. b NR; MIC not reached, isolate could grow at highest concentration of antibiotic tested.