Figure 4

Neutralization assay of HCV infection with MT81 and MT81 w antibodies. HCVcc (A) and HCVpp 2a (B) infections of Huh-7w7/mCD81 cells were performed in presence of indicated concentrations of MT81 (left panels) or MT81w (right panels) mAbs or in presence of 30 μg/ml of transferrin receptor (right panels, TR30). At 2 days post-infection, cells were lysed and processed as described in methods. P < 0.05 as calculated by the Mann-Whitney's test.