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Table 1 Summary of interactions of RhoGDIs with Rho GTPases. Interaction of TbRhoGDI and LyGDI with Rho GTPases was determined using a yeast two-hybrid assay (Fig. 5A). Interaction of bovine RhoGDI with the indicated Rho GTPases was determined in translocation experiments (Fig. 5C). Data on Dictyostelium RhoGDI1 was taken from Rivero et al. [23], except for the interactions with TbCdc42 and ScCdc42. DdRacF1 was used in yeast two-hybrid experiments, whereas DdRacF2 was used in translocation experiments. NA, not assayed.

From: Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus Tuber borchii

 

TbRhoGDI

RhoGDI

LyGDI

DdRhoGDI1

TbCdc42

+

NA

+

+

ScCdc42

-

NA

+

+

DdRac1a

+

+

+

+

DdRac1b

+

NA

+

+

DdRac1c

+

NA

+

+

DdRacB

-

+

+

+

DdRacC

-

+

-

+

DdRacE

-

+

-

+

DdRacF1 or F2

-

-

-

-

HsRac1

-

+

+

+

HsRhoA

-

+

+

+

HsCdc42

+

+

+

+