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Table 1 Association of the rlrA islet with serotypes and PFGE clusters

From: The presence of the pilus locus is a clonal property among pneumococcal invasive isolates

Serotype

OR (95% CI)a

p

STs in PFGE clusterb

OR (95% CI)

p

1

0.22 (0.07 – 0.53)

0.0011

[ST306 + ST228]

0.079 (0.01 – 0.59)

0.0007

3

NSc

 

[ST1220 + ST260] + [ST1230 + ST180]

0.06 (0.01 – 0.44)

< 10-4

4

12.74 (5.05 – 32.12)

< 10-4

ST1221

80.26 (4.72 – 1363.4)

< 10-4

   

ST247

30 (3.8 – 236.84)

< 10-4

6B

7.44 (2.29 – 24.16)

0.0005

ST1224 + ST273

47.33 (2.7 – 830.37)

< 10-4

7F

0 (0 – 0.61)

0.0052

ST191

0 (0.0 – 0.70)

0.0089

8

0 (0 – 0.37)

0.0002

ST53

0 (0.0 – 0.57)

0.0057

9V

14.36 (4.76 – 43.33)

< 10-4

[ST156 + ST557 + ST644 + ST1225]

16.76 (4.80 – 58.54)

< 10-4

12B

0 (0 – 0.70)

0.0089

NSc

NSc

 

14

16.13 (8.50 – 30.63)

< 10-4

[ST156 + ST557 + ST790]

212.4 (28.89 – 1561.8)

< 10-4

23F

0 (0 – 0.44)

0.0006

ST338 + ST1371

0 (0.0 – 0.57)

0.0057

  1. aAn OR of > 1 indicates increased proportion of rlrA positive isolates whereas OR of < 1 indicates decreased proportion of rlrA positive isolates. Only statistically significant results (FDR < 0.05) are presented.
  2. bSTs in PFGE clusters with a Dice similarity coefficient of > 80%. Brackets indicate STs that belong to the same lineage, as defined by eBURST analysis with the complete S. pneumoniae database available at spneumoniae.mlst.net. Only statistically significant results (FDR < 0.05) are presented.
  3. cNS – not significant