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Figure 1 | BMC Microbiology

Figure 1

From: Uptake and intra-inclusion accumulation of exogenous immunoglobulin by Chlamydia-infected cells

Figure 1

IgG is present throughout the course of infection. Selected time points throughout the course of a 72 h C. trachomatis serovar K infection in J774A.1 macrophages each show IgG to be co-localized with the chlamydial inclusion. FITC-labeled anti-bovine IgG antibodies (green) heavily co-localize with TRITC-labeled chlamydial antigens (red) at all observed timepoints, suggesting IgG is present during various stages of the chlamydial developmental cycle. A typical uninfected cell, detected by DAPI staining, is evident in the merge panel of the 48 hpi series and shows no antigen-specific recognition by the rabbit anti-Chlamydia or goat anti-bovine IgG antibodies. (bar = 15 μm).

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