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Table 1 Immune response genes differentially expressed after infection with pYV+ compared to ΔyopH

From: Role of IFN-gamma and IL-6 in a protective immune response to Yersinia enterocoliticain mice

 

pYV+ (5 × 103)

pYV+ (5 × 104)

ΔyopH(5 × 104)

ΔyopH(5 × 106)

 

fold expression compared to uninfected

fold expression compared to uninfected

fold expression compared to uninfected

fold expression compared to uninfected

Group 1

    

A

    

CXCL2

39.4

45.3

7.5

36.8

CCL2

13

22.6

4.6

48.5

Histidine decarboxylase

3.5

3.8

1.2

4

IFN-γ

12.1

36.8

3.0

13.3

IL-12A

21.1

36.8

1.2

8.6

TNF-α

9.9

10.6

4

10.6

B

    

IL6

19.7

32.0

9.2

5.2

INOS

4.6

3.7

1.3

1.7

IL1A

90.5

119.4

14.9

26.0

CXCL1

12.1

21

3

7

Group 2

    

A

    

SAA3

1.1

1.3

0.4

3.5

Lactotransferrin

0.4

0.5

0.3

2.8

LBP

0.8

1

0.5

2.8

MARCO

0.6

0.4

1.7

8.6

Orosomucoid

0.4

0.7

0.7

3.3

Peptidoglycan recognition protein

0.6

0.9

0.8

2.6

B

    

CCL17

2.1

10.6

1.2

6.5

IL10

1.2

4

2

8.6

Group 3

    

CXCL9

21.1

14.9

9.2

3.7

IIGP1

32

39.4

24.3

8.6

MX1

6.5

6.5

4

1.2

WARS

4.6

3.7

4.6

1.9

VEGFA

6.5

6.5

5.7

2.3