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Figure 5 | BMC Microbiology

Figure 5

From: Altered cellular infiltration and cytokine levels during early Mycobacterium tuberculosis sigC mutant infection are associated with late-stage disease attenuation and milder immunopathology in mice

Figure 5

Cytokine profiles detected in the lung tissue homogenates of SCID mice infected separately with the three different M. tb strains. Supernatants were collected from lung homogenates of SCID mice which were infected with the ΔsigC mutant strain (◇), the ΔsigC complemented mutant (△) and the wild type strain, CDC1551 (□). Mice were sacrificed at days 1, 14, 21 and 28 after infection. Each time point represents data from 5 mice and each were performed in triplicate. (* = p < 0.05; ** = p < 0.01; *** = p < 0.001).

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