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Table 1 Genes upregulated at least twofold at 37°C relative to 28°C

From: Genome-wide transcriptional analysis of temperature shift in L. interrogans serovar lai strain 56601

Gene ID

Gene function and name

Fold change in

  

Expt1

Expt2

Cell wall/membrane biogenesis genes

LA1203

alginate o-acetyltransferase

2.393

2.084

LA3927

Outer membrane protein tolC precursor

3.337

3.817

Posttranslational modification, heat shock proteins genes

LA1563

class II heat shock protein (HSP20)

2.439

4.233

LA1564

class II heat shock protein (HSP20)

2.142

2.859

replication, DNA repair, transcription and translation genes

LA0877

Probable RNA polymerase ECF-type sigma factor

4.704

4.752

LA0878

DshA protein

3.305

3.076

LA2204

hypothetical protein

2.027

3.693

LA3749

hypothetical protein

2.200

4.771

LA0065

DNA-damage-inducible protein F

2.356

2.028

Signal transduction mechanism genes

LA2549

Sensory transduction histidine kinase

3.174

2.309

intracellular trafficking and secretion genes

LA0905

hypothetical protein

9.108

7.718

LA3927

Outer membrane protein tolC precursor

3.337

3.817

metabolism genes

LA0633

Probable peptide transporter permease

2.441

2.025

LA3498

Phosphate transport system protein phoU

2.934

4.779

LA0430

hypothetical protein

7.594

4.995

LA1889

Putative 1-aminocyclopropane-1-carboxylate deaminase

2.692

2.519

general function

LA0297

CBS domain protein

2.464

2.200

LA0450

conserved hypothetical protein

2.631

2.244

LA0700

hypothetical protein

3.174

2.309

unknown

LA2440

hypothetical protein

2.309

2.956

LA2727

unknown protein

2.212

2.030

LA0430

hypothetical protein

7.594

4.995

LA1809

conserved hypothetical protein

2.155

2.882

LA2465

unknown protein

2.284

3.392

LA2764

hypothetical protein

6.620

7.058

LA4191

hypothetical protein

2.063

2.936