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Figure 2 | BMC Microbiology

Figure 2

From: Evidence from bioinformatics, expression and inhibition studies of phosphoinositide-3 kinase signalling in Giardia intestinalis

Figure 2

PI3K domain pairwise alignments for GiPI3K1 and GiPI3K2. Pairwise sequence alignment of GiPI3K1 and GiPI3K2 indicates conservation in predicted Ras Binding (a), C2 (b) and PIK (c) domains. Identical aligned residues are indicated in black shading, while conserved residues are indicated by grey shading according to the PAM250 matrix [45]. Identity/similarity percentages for the GiPI3K1 alignments are 15%/45%, 12%/31% and 20%/51% for the GiPI3K1 RBD, C2 and PIK domains respectively, for the GiPI3K2 alignments these values are 13%/31% and 16%/47% for the GiPI3K2 C2 and PIK domains respectively.

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