Figure 9

Ebola virus induces increased PML expression in the infected cells. Double immunofluorescence staining of VP40 and VP35 in MCF7 or NP in Vero E6 cells (red) with PML (green) 48 hrs post-infection. The pictures shows that infected cells express more PML proteins as compared to the non-infected neighbouring cells. DNA staining is blue. The intensity of the PML fluorescence signal is not directly comparable between Vero E6 (weak overall PML staining) and MCF7 cells (strong overall PML staining).