Figure 2

Internet database interrogation page . The query page can be accessed via http://bacterial-genotyping.igmors.u-psud.fr/bnserver. The home page (not shown) includes a link to help files (and data updates information), and links to individual species query pages. Currently, identification pages are available for Y. pestis, B. anthracis (based on the data published in [1] and some additional unpublished data) and M. tuberculosis. Figure 2 shows the current M. tuberculosis query page. For each marker, allele sizes can be selected among the list of observed sizes. Allele sizes are indicated either as number of motifs, or as fragment sizes, assuming that the primers used are the primers listed in Table 2. The allele size listed in green corresponds to the H37RV control strain allele. More experienced users can go directly to a page on which data (expressed in base-pairs or in repeat unit number) can be directly pasted using the appropriate format.