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Figure 1 | BMC Microbiology

Figure 1

From: HIV-1 expression induces cyclin D1 expression and pRb phosphorylation in infected podocytes: cell-cycle mechanisms contributing to the proliferative phenotype in HIV-associated nephropathy

Figure 1

In situ immunodetection of phosphorylated serine 780 on pRb in Tg26 kidneys. Phospho-pRb (Ser780) is not detected in the nuclei of epithelium of normal kidneys (A), but is readily detected in podocytes (short arrows) and tubular epithelial cells (long arrows) in hyperplastic nephrons of diseased transgenic kidneys at cortical (B), juxta-medullary (C), and medullary (D) depths. The prominent staining in many, but not all nuclei, is characteristic of asynchronously proliferating cells. (magnification = 40×)

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BMC Microbiology

ISSN: 1471-2180

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