Table 7 Modifications detected in gene VC_A0531 ( kdpD ) by PCR analysis of 15 resistant mutants (AA, amino acid)
Nucleotide pos. | Ref. allel | Mut. allel | Number of mutants | Codon old | Codon new | AA pos. | AA old | AA new | |
|---|---|---|---|---|---|---|---|---|---|
1 | 218 | T | C | 1 | CUA | CCA | 73 | Leu | Pro |
2 | 848 | C | T | 4 | ACG | AUG | 283 | Thr | Met |
3 | 1,022 | C | A | 1 | CCU | CAU | 341 | Pro | His |
4 | 1,177 | G | A | 1 | GAA | AAA | 393 | Glu | Lys |
5 | 1,178 | A | G | 1 | GAA | GGA | 393 | Glu | Gly |