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Table 4 (Putative) virulence factors of strain W12-1067

From: Genome sequence and phenotypic analysis of a first German Francisella sp. isolate (W12-1067) not belonging to the species Francisella tularensis

Name

Peg Nr.

Feature

Closest homolog

MglA

693

Macrophage growth locus protein

FTN_1290 (82%)

CapBCA

74-76

Capsular biosynthesis

Fphi_1486-88 (nd)

FeoB

1092

Ferrous iron transport protein

FTN_0066 (82%)

PilT

1248

Twitching motility protein

FTN_1622 (94%)

DeoB

802

Phosphopentomutase

FN3523_1666 (80%)

BipA

325

GTP-binding protein

Fphi_0048 (91%)

SurA

543

Peptidyl-prolyl cis-trans isomerase

FTN_0559 (69%)

MviN

843

Flippase

FTN_0276 (61%)

HlyB

1149

Toxin secretion ABC transporter

FTN_1693 (74%)

Phospholipase

743

Lecithinase/hemolysin

FTN_0436 (75%)

Lysophospholipase

167

Lysophospholipase

Fphi_1625 (67%)

HlyC/CorC

182

CBS domain, putative hemolysin

FTN_1006 (80%)

ClpB

1114

ClpB chaperone domain

FTN_1743 (89%)

Chitinase 1 (372 aa)

490

GH18_chitinase-like superfamily

Fphi_0209 (83%)

Chitinase 2 (590 aa)

816

Chitinase_glyco-hydro_19 domain, PP location, CBM

Fphi_0512 (69%)

Chitinase 3 (437 aa)

818

Chitinase_glyco-hydro_19 domain, SP

Fphi_0512 (70%)

Chitinase 4 (979 aa)

1009

GH18_chitinase-like superfamily, SP, two internal repeats

FTW_0142 (55%)

Chitinase 5 (731 aa)

1044

GH18_chitinase-like superfamily, SP, EC location, 2 × CBMn

FN3523_1814 (49%)

Chitinase 6 (843 aa)

1477

GH18_chitinase-like superfamily, SP, EC location, 2 × CBM

Fphi_0208 (55%)

Hypothetical protein

523

Ankyrin repeat, Ank_2 domain

---

Hypothetical protein

567

Ankyrin repeat, Ank_2 domain

---

Hypothetical protein

1109

Ankyrin repeat, Ank_4 domain

---

Hypothetical protein

173

TPR domain

FTW_0991 (63%)

Hypothetical protein

1024

TPR domain

Fphi_0624 (69%)

Hypothetical protein

1030

TPR domain, TPR_16

FTM_1557 (72%)

  1. SP, signal peptide; EC, extracellular; PP, periplasmic; CBM, carbohydrate binding motif; TPR, tetratricopeptide repeat.