BMC Microbiology

Table 1 Genetic characterization of genes associated with KM resistance of KM-resistant and KM-susceptible M. tuberculosis strains

From: Molecular characterization of amikacin, kanamycin and capreomycin resistance in M/XDR-TB strains isolated in Thailand

No. of strains	MIC (μg/ml)			Gene/Mutation
	AK	KM	CAP	rrs	eis	tap	whiB7	tlyA
KM resistant (29)
1	>64	>64	>64	A1401G	wt	Ins581C	wt	A33G^b
7	>64	>64	32	A1401G	wt	Ins581C	wt	A33G^b
5	>64	>64	32	A1401G	wt	wt	wt	A33G^b
4^a	>64	>64	16	A1401G	wt	Ins581C	wt	A33G^b
2	>64	>64	16	A1401G	wt	wt	wt	A33G^b
1	>64	>64	4	A1401G	wt	Ins581C	wt	A33G^b
1	8	32	8	A1401G	wt	Ins581C	wt	A33G^b
1	8	>64	8	wt	C-14 T	Ins581C	wt	A33G^b
1	8	>64	>64	wt	C-14 T	Ins581C	wt	A33G^b/Ins49GC
2^a	8	>64	>64	wt	C-14 T	Ins581C	wt	A33G^b/T539G
1	8	>64	>64	wt	G-37 T	Ins581C	wt	A33G^b
2	>64	>64	16	wt	wt	Ins581C	wt	A33G^b
1^a	>64	>64	16	wt	wt	wt	wt	A33G^b
KM susceptible (27)
5	2-4	4	2-4	wt	wt	Ins581C	wt	A33G^b
22	2-4	4	2-4	wt	wt	wt	wt	A33G^b

^ainclude one MDR-TB strain; ^bno amino acid change.

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ISSN: 1471-2180

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