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Table 1 Differential mRNA expressions of molecules in JNK1/2 and p38 MAPK signaling pathways in EV71-infected iDCs at different time points

From: Activation of JNK1/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells

Gene symbol

EV71/control (Fold changes)

1/2 h

2 h

8 h

24 h

MAP2K3 (MEK3)

+1.58

+3.08

+1.13

+1.05

MAP2K4 (MEK4)

+1.25

+1.16

+2.05

-1.11

MAP2K6 (MEK6)

-1.08

+2.30

+1.76

+1.08

MAP2K7 (MEK7)

+1.61

+1.10

+2.75

+1.00

MAPK8 (JNK1; SAPK1)

+1.27

+2.30

+1.10

+1.40

MAPK9 (JNK2; SAPK)

+1.14

+1.31

+2.59

+1.18

MAPK10 (JNK3)

+1.89

+1.94

+2.51

-1.80

MAPK11 (p38-β MAPK)

+1.10

+2.81

+1.72

+1.01

MAPK12 (p38–γ MAPK)

+1.28

+1.06

+1.76

+1.25

MAPK13 (p38 -δ MAPK)

+1.39

-1.54

-1.15

-1.01

MAPK14 (p38-α MAPK)

+1.36

+1.30

+2.02

+1.19

c-Jun

+1.28

+1.89

+3.03

+3.30

c-Fos

+9.17

+8.12

+4.05

+3.32

IFN-α1

-1.04

+1.79

+1.24

-2.15

IFN-β

-1.10

+2.24

+1.68

-2.02

IL-2

-1.09

+4.32

+1.40

-4.88

IL-6

-1.27

+2.83

-1.73

-1.25

IL-10

-1.06

+1.91

+1.14

+1.18

IL-12

+1.01

+1.22

+2.67

+1.49

TNF-α

+1.59

+2.44

+1.45

+1.74

  1. Upregulated and downregulated transcripts are indicated as ‘+’ and ‘–’ values, respectively. The changes of mRNA expressions (≥2 or ≤-2 – fold) are indicated by boldface letters.