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Figure 5 | BMC Microbiology

Figure 5

From: Identification of natural antimicrobial agents to treat dengue infection: In vitro analysis of latarcin peptide activity against dengue virus

Figure 5

Mode of action of the Ltc 1 peptide against DENV2 infection. (A) The DENV2 viral load for the pre-, simultaneous and post-infection treatments with the latarcin peptide. The viral load (pfu/ml) was significantly reduced for the pre-treatment (4.5 ± 0.6 vs. 6.9 ± 0.5 control), simultaneous (0.7 ± 0.3 vs. 7.2 ± 0.5 control) and post-treatment (1.8 ± 0.7 vs. 6.8 ± 0.6 control) (two-way ANOVA with Bonferroni post-test). (B) The viral loads in the infected HepG2 cells of the pre-, simultaneous and post-infection treatments were quantified and calculated based on plaque formation in Vero cells after a five-day incubation.

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BMC Microbiology

ISSN: 1471-2180

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