Identification of leptospiral 3-hydroxyacyl-CoA dehydrogenase released in the urine of infected hamsters

BMC Microbiology

Table 1 List of hamster proteins excreted in urine that had increased levels of expression during infection

Spot no.	Accession no.†	Protein annotation	MW (kDa)	pI	Urinary marker of diseases (Reference)
28	gi:110347564	ceruloplasmin isoform b [Mus musculus]	121872	5.53	Acute renal transplant rejection [29, 30]
29	gi:83816939	alpha-1-inhibitor III [Rattus norvegicus]	165038	5.7	No reports
30, 32, 33, 38	gi:58585560	albumin [Microtus fortis fortis]	70261	5.91	Glomerular disease [31, 32], Diabetes mellitus type 2 [33]
31	gi:17046471	transferrin [Mus musculus]	78794	6.92	Glomerular disease [31, 32]
34	gi:68052028	Alpha-1-antitrypsin precursor	46019	5.55	Glomerular disease [32]
35	gi:191388	pregnancy protein 60 kDa	47574	8.53	No reports
36	gi:19705570	angiotensinogen [Rattus norvegicus]	52177	5.37	Chronic kidney disease [34]
37	gi:193446	vitamin D-binding protein [Mus musculus]	54647	5.26	Glomerular disease [31, 32]
39-41	gi:41019123	Haptoglobin precursor	39090	5.76	Glomerular disease [31, 32], Diabetes mellitus type 2 [33]
42	gi:2497695	AMBP protein precursor	39669	5.87	Diabetes mellitus type 2 [33, 35]
43-45, 48	gi:62899898	Apolipoprotein A-I precursor	30720	5.86	Glomerular disease [36]
46, 51, 52	gi:6981420	pancreatic trypsin 1 [Rattus norvegicus]	26627	4.71	Pancreatitis [31]
47, 49	gi:16716569	protease, serine, 1 [Mus musculus]	26802	4.75	No reports
50, 53, 54	gi:6981684	transthyretin [Rattus norvegicus]	15852	5.77	Glomerular disease [31, 32], Diabetes mellitus type 2 [33]
55	gi:226471	Cu/Zn superoxide dismutase	15923	6.03	Endemic nephropathy [37]

ISSN: 1471-2180