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Figure 4 | BMC Microbiology

Figure 4

From: Immunobiotic Lactobacillus rhamnosus strains differentially modulate antiviral immune response in porcine intestinal epithelial and antigen presenting cells

Figure 4

Effect of immunobiotic lactobacilli in porcine antigen presenting cells (APCs) from Peyer’s patches co-cultured with porcine intestinal epithelial (PIE) cells. PIE cells were co-cultured with adherent cells from Peyer’s patches and stimulated with Lactobacillus rhamnosus CRL1505 (Lr1505) or L. rhamnosus CRL1506 (Lr1506) for 12 hours. PIE-APCs co-cultures were then challenged with poly(I:C). The mRNA expression of IFN-α, IFN-β, IL-1β, TNF-α, IFN-γ, IL-6, IL-2, IL-12, IL-10 and TGF-β was studied at different time points after challenge. Cytokine mRNA levels were calibrated by the swine β-actin level and normalized by common logarithmic transformation. Values represent means and error bars indicate the standard deviations. The results are means of 3 measures repeated 4 times with independent experiments. The mean differences among different superscripts letters were significant at the 5% level.

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