RMS | Mean ± SD frequency/1,000 bp | O/E ratiob | |||||
---|---|---|---|---|---|---|---|
Endonuclease/ Methylase | Cognate recognition sitea | Observed | Expected | Observed | Expected | MLS (N = 73) | WGS (N = 6) |
Hpy166III | CCTC | 2.7 + 0.41 | 5.49 + 0.07 | 2.93 + 0.02 | 4.50 + 0.03 | 0.50 c | 0.65 |
Hpy178VI | GGATG | 1.48 + 0.23 | 1.59 + 0.03 | 0.81 + 0.00 | 1.37 + 0.01 | 0.93 | 0.59 |
Hpy178VII | GGCC | 1.24 + 0.31 | 1.96 + 0.05 | 0.98 + 0.02 | 1.43 + 0.02 | 0.63 | 0.68 |
Hpy188I | TCNGA | 1.02 + 0.21 | 3.70 + 0.03 | 0.81 + 0.02 | 3.53 + 0.01 | 0.28 | 0.23 |
Hpy188III | TCNNGA | 1.11 + 0.22 | 3.70 + 0.04 | 1.19 + 0.02 | 3.53 + 0.01 | 0.30 | 0.34 |
Hpy8I | GTNNAC | 0.40 + 0.35 | 3.70 + 0.03 | 0.22 + 0.01 | 3.53 + 0.01 | 0.11 | 0.06 |
Hpy8II | GTSAC | 0.00 + 0.00 | 1.56 + 0.02 | 0.05 + 0.00 | 1.37 + 0.01 | 0.00 | 0.04 |
Hpy8III | GWGCWC | 0.07+ 0.12 | 0.66 + 0.01 | 0.19 + 0.01 | 0.54 + 0.00 | 0.10 | 0.36 |
Hpy99I | CGWCG | 0.28 + 0.06 | 1.13 + 0.02 | 0.15 + 0.01 | 0.88 + 0.01 | 0.25 | 0.17 |
Hpy99III | GCGC | 4.62 + 0.64 | 1.96 + 0.05 | 3.73 + 0.11 | 1.43 + 0.02 | 2.36 | 2.60 |
Hpy99IV | CCNNGG | 1.62 + 0.26 | 1.96 + 0.05 | 0.70 + 0.01 | 1.43 + 0.03 | 0.83 | 0.49 |
Hpy99VIP | GATC | 5.48 + 0.44 | 3.70 + 0.03 | 3.19 + 0.04 | 3.53 + 0.01 | 1.48 | 0.90 |
Hpy99XIIP | GTAC | 0.37 + 0.20 | 3.70 + 0.04 | 0.07 + 0.00 | 3.53 + 0.01 | 0.10 | 0.02 |
HpyAV | CCTTC (6/5) | 0.58 + 0.12 | 1.58 + 0.02 | 0.80 + 0.02 | 1.37 + 0.01 | 0.37 | 0.58 |
HpyC1I | CCATC(4/5) | 1.94 + 0.26 | 1.60 + 0.02 | 1.39 + 0.01 | 1.37 + 0.01 | 1.22 | 1.01 |
HpyCH4II | CTNAG | 0.60 + 0.28 | 3.70 + 0.03 | 1.84 + 0.04 | 3.53 + 0.01 | 0.16 | 0.52 |
HpyCH4III | ACNGT | 0.89 + 0.22 | 3.70 + 0.04 | 0.34 + 0.00 | 3.53 + 0.01 | 0.24 | 0.10 |
HpyCH4IV | ACGT | 0.39 + 0.22 | 3.70 + 0.04 | 0.18 + 0.01 | 3.53 + 0.01 | 0.11 | 0.05 |
HpyCH4V | TGCA | 3.85 + 0.75 | 3.70 + 0.03 | 3.45 + 0.03 | 3.53 + 0.03 | 1.04 | 0.98 |
HpyCI | GATATC | 0.00 + 0.03 | 0.31 + 0.01 | 0.02 + 0.00 | 0.33 + 0.00 | 0.01 | 0.07 |
HpyF10VI | GCNNNNNNNGC | 2.70 + 0.35 | 1.96 + 0.04 | 2.97 + 0.09 | 1.43 + 0.02 | 1.38 | 2.07 |
HpyF14I | CGCG | 2.26 + 0.46 | 1.96 + 0.05 | 1.55 + 0.05 | 1.43 + 0.02 | 1.15 | 1.08 |
HpyF2I | CTRYAG | 1.16 + 0.17 | 0.92 + 0.01 | 0.37 + 0.01 | 0.88 + 0.00 | 1.26 | 0.42 |
HpyF36IV | GDGCHC | 0.20 + 0.21 | 1.22 + 0.03 | 0.31 + 0.01 | 0.93 + 0.01 | 0.16 | 0.33 |
HpyF44II | GGNNCC | 1.21 + 0.38 | 1.96 + 0.05 | 0.44 + 0.00 | 1.43 + 0.02 | 0.62 | 0.31 |
HpyII | GAAGA | 2.29 + 0.23 | 2.14 + 0.03 | 2.87 + 0.02 | 2.16 + 0.00 | 1.07 | 1.33 |
HpyIP | CATG | 4.63 + 0.25 | 3.70 + 0.03 | 4.43 + 0.04 | 3.53 + 0.01 | 1.25 | 1.25 |
HpyIV | GANTC | 1.70 + 0.25 | 3.70 + 0.04 | 1.66 + 0.02 | 3.53 + 0.01 | 0.46 | 0.47 |
HpyNI | CCNGG | 2.04 + 0.30 | 1.96 + 0.05 | 0.87 + 0.02 | 1.43 + 0.02 | 1.04 | 0.61 |
HpyPORF1389P | GAATTC | 0.01 + 0.05 | 0.31 + 0.01 | 0.11 + 0.00 | 0.33 + 0.00 | 0.03 | 0.32 |
HpyV | TCGA | 0.95 + 0.25 | 3.70 + 0.03 | 0.18 + 0.00 | 3.53 + 0.01 | 0.26 | 0.05 |
HpyVIII | CCGG | 1.92 + 0.30 | 1.96 + 0.04 | 1.06 + 0.02 | 1.43 + 0.02 | 0.98 | 0.74 |