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Figure 6 | BMC Microbiology

Figure 6

From: Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB

Figure 6

Direct delivery of T3SS3 mutant into the cytosol activates NFκB. NFκB/293/GFP-Luc cells were injected with wildtype B. thailandensis (E264) (A) or B. thailandensis ΔbsaS (B) for 6 hr or 24 hr (C, D). The infected cells were observed under the fluorescence microscope (40x magnification for 6 hr and 10x magnification for 24 hr) to monitor for GFP production as an indication of NFκB activation. The right panel represents an image taken under bright field microscope illumination whereas the left panel shows an image taken under fluorescence illumination.

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