Skip to main content

Table 2 Experimental design

From: Effects of the probiotic Lactobacillus animalis in murine Mycobacterium avium subspecies paratuberculosis infection

Experimental Groups

Time-Points (Number of Animals per sex M/F)

Key to Abbreviated Terms for Experimental Groups

Conditions Describing Experimental Group

 

Day 45

Day 90

Day 135

Day 180

  

Control*

(5/5)

(5/5)

(5/5)

(5/5)

C = Control

No-MAP infection; No- probiotics in diet

L-MAP*

(5/5)

(5/5)

(5/5)

(5/5)

L-MAP = Viable MAP

MAP infection; No probiotics in diet

K-MAP

(5/5)

(5/5)

(5/5)

(5/5)

K-MAP = Non-viable MAP

Non-viable MAP antigen; No probiotics in diet

L-NP-51*

(5/5)

(5/5)

(5/5)

(5/5)

L-NP-51 = Viable Probiotics

No-MAP infection; probiotics in diet

L-MAP + L-NP-51*

(5/5)

(5/5)

(5/5)

(5/5)

L-MAP + L-NP-51= Viable MAP & Probiotics

MAP infection; probiotics in diet

K-MAP + L-NP-51*

(5/5)

(5/5)

(5/5)

(5/5)

K-MAP + L-NP-51 = Non- Viable MAP & Viable Probiotics

Non-viable MAP antigen; probiotics in diet

K-NP-51

(5/5)

(5/5)

(5/5)

(5/5)

K-NP-51= Non-viable Probiotics

Non-viable probiotics in diet

Maltodextrin

(5/5)

(5/5)

(5/5)

(5/5)

MD= Maltodextrin

Filler material in diet

K-MAP + K-NP-51

(5/5)

(5/5)

(5/5)

(5/5)

K-MAP + K-NP-51 = Non- viable MAP & Non-viable NP-51

Non-viable MAP antigen; non-viable probiotics in diet

L-MAP + K-NP-51

(5/5)

(5/5)

(5/5)

(5/5)

L-MAP + K-NP-51

Viable- MAP antigen; and non- viable probiotics in diet

Total Animals Per Time Point  100

  1. A description of each of the experimental groups, sexes, and treatments are described for one time point, each of the four time points in this study had the same experimental design. Select experimental groups were analyzed for metagenomic, transcriptomic and cytokine analysis based on histopathology results; the selected groups’ are highlighted with '*'.